RNA: primed for packing?
نویسندگان
چکیده
How does RNA's seemingly subtle 2'-hydroxyl group contribute to its diverse biological functions? Using quantitative structure-activity relationship (QSAR) analysis, Piccirilli and colleagues find that the 2'-OH fosters van der Waals and hydrophobic interactions that play underappreciated roles in RNA structure and molecular recognition.
منابع مشابه
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عنوان ژورنال:
- Chemistry & biology
دوره 11 2 شماره
صفحات -
تاریخ انتشار 2004